Is there a downside to having multiple credit cards open?

No. Having multiple credit cards can actually improve your credit score by lowering utilization and increasing available credit.

Do I need to spend a minimum each month to qualify for travel benefits?

Most cards do not require a monthly minimum. Some cards have annual spending thresholds, like $75,000 on the Amex Platinum for extra lounge guest access.

How long before a trip should we reach out?

The earlier the better. Airlines publish schedules 11–12 months out, and while award seats aren’t always released immediately, it helps to plan ahead.